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randomized, controlled, open label non-inferiority trial of intravenous ferric carboxymaltose versus ironsucrose in patients with iron deficiency anemia in China

Frontiers of Medicine doi: 10.1007/s11684-023-1001-2

Abstract: Iron deficiency (ID) and ID anemia (IDA) pose significant public health concerns in China.Although iron sucrose (IS) treatment is well-established in the country, ferric carboxymaltose (FCM)conducted at multiple sites in China to compare the outcomes of FCM (maximum of 2 doses, 500 or 1000 mg iron) and IS (up to 11 infusions, 200 mg iron) treatments in subjects with IDA.

Keywords： iron deficiency     anemia     intravenous iron     ferric carboxymaltose     iron sucrose     Hb response     early response    

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Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:

Dong Wang, Min Tian, Guanglin Cui, Dao Wen Wang

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 319-323 doi: 10.1007/s11684-017-0553-4

Abstract: Mutations in and lead to deficiency or dysfunction of the two proteins, which could result in venousCoagulation tests revealed that the patient presented type I antithrombin deficiency combined with decreasedThis study demonstrates that the combination of antithrombin deficiency and decreased protein C activity

Keywords： antithrombin deficiency     protein C activity     mutation     variant     venous thromboembolism     anticoagulants    

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Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice

Frontiers of Medicine   Pages 957-971 doi: 10.1007/s11684-023-0988-8

Abstract: To the best of our knowledge, this study is the first to report DNAH10 deficiency related to PCD

Keywords： DNAH10     mice     motile cilia     mutation     primary ciliary dyskinesia    

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Prevalence of vitamin D deficiency in girls with idiopathic central precocious puberty

Yue Zhao, Wenjun Long, Caiqi Du, Huanhuan Yang, Shimin Wu, Qin Ning, Xiaoping Luo

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 174-181 doi: 10.1007/s11684-017-0544-5

Abstract:

The relationship between vitamin D deficiency and idiopathic central precocious puberty (ICPP) hasThe ICPP subjects with 25[OH]D deficiency had a higher body mass index (BMI) than the subjects from the

Keywords： idiopathic central precocious puberty     threshold effects     vitamin D status    

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Synergistic effects of sodium hypochlorite disinfection and iron-oxidizing bacteria on early corrosionin cast iron pipes

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 6, doi: 10.1007/s11783-021-1506-3

Abstract:

• The early corrosion process in the cast iron pipes was investigated

Keywords： Cast iron pipe corrosion     Drinking water distribution systems     Chlorine disinfection     Iron-oxidizing    

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Intestinal Epithelial Axin1 Deficiency Protects Against Colitis via Altered Gut Microbiota

Shari Garrett,Yongguo Zhang,Yinglin Xia,Jun Sun,

Engineering doi: 10.1016/j.eng.2023.06.007

Abstract: Intestinal homeostasis is maintained by specialized host cells and the gut microbiota. Wnt/β-catenin signaling is essential for gastrointestinal development and homeostasis, and its dysregulation has been implicated in inflammation and colorectal cancer. Axin1 negatively regulates activated Wnt/β-catenin signaling, but little is known regarding its role in regulating host–microbial interactions in health and disease. Here, we aim to demonstrate that intestinal Axin1 determines gut homeostasis and host response to inflammation. Axin1 expression was analyzed in human inflammatory bowel disease datasets. To explore the effects and mechanism of intestinal Axin1 in regulating intestinal homeostasis and colitis, we generated new mouse models with Axin1 conditional knockout in intestinal epithelial cell (IEC; Axin1ΔIEC) and Paneth cell (PC; Axin1ΔPC) to compare with control (Axin1LoxP; LoxP: locus of X-over, P1) mice. We found increased Axin1 expression in the colonic epithelium of human inflammatory bowel disease (IBD). Axin1ΔIEC mice exhibited altered goblet cell spatial distribution, PC morphology, reduced lysozyme expression, and enriched Akkermansia muciniphila (A. muciniphila). The absence of intestinal epithelial and PC Axin1 decreased susceptibility to dextran sulfate sodium-induced colitis in vivo. Axin1ΔIEC and Axin1ΔPC mice became more susceptible to dextran sulfate sodium (DSS)-colitis after cohousing with control mice. Treatment with A. muciniphila reduced DSS-colitis severity. Antibiotic treatment did not change the IEC proliferation in the Axin1Loxp mice. However, the intestinal proliferative cells in Axin1ΔIEC mice with antibiotic treatment were reduced compared with those in Axin1ΔIEC mice without treatment. These data suggest non-colitogenic effects driven by the gut microbiome. In conclusion, we found that the loss of intestinal Axin1 protects against colitis, likely driven by epithelial Axin1 and Axin1-associated A. muciniphila. Our study demonstrates a novel role of Axin1 in mediating intestinal homeostasis and the microbiota. Further mechanistic studies using specific Axin1 mutations elucidating how Axin1 modulates the microbiome and host inflammatory response will provide new therapeutic strategies for human IBD.

Keywords： Axin1     Bacteria     Microbiome inflammation     Inflammatory bowel disease     Immunity     Microbiome     Paneth cells     Akkermansia muciniphila     Wnt    

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Chinmedomics facilitated quality-marker discovery of Sijunzi decoction to treat spleen qi deficiency

Qiqi Zhao, Xin Gao, Guangli Yan, Aihua Zhang, Hui Sun, Ying Han, Wenxiu Li, Liang Liu, Xijun Wang

Frontiers of Medicine 2020, Volume 14, Issue 3,   Pages 335-356 doi: 10.1007/s11684-019-0705-9

Abstract: Sijunzi decoction (SJZD) is a Chinese classical formula to treat spleen qi deficiency syndrome (SQDS)

Keywords： traditional Chinese medicine     Sijunzi decoction     spleen qi deficiency syndrome     Chinmedomics     quality-marker    

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Performance of iron-air battery with iron nanoparticle-encapsulated C–N composite electrode

Frontiers in Energy doi: 10.1007/s11708-023-0913-5

Abstract: Highly efficient and stable iron electrodes are of great significant to the development of iron-air batteryIn this paper, iron nanoparticle-encapsulated C–N composite (NanoFe@CN) was synthesized by pyrolysisNeutral K2SO4 electrolyte can effectively suppress the passivation of iron electrodeCompared to the pure nano-iron (NanoFe) battery, the NanoFe@CN battery has a more stable cycling stability

Keywords： energy storage and conversion     metallic composites     nanocomposites     iron-air battery     iron anode    

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Redox reactions of iron and manganese oxides in complex systems

Jianzhi Huang, Huichun Zhang

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 5, doi: 10.1007/s11783-020-1255-8

Abstract: . • Reductive reaction of Fe(II)/iron oxides in complex systems was examined. • Future research on examiningfocused on (1) the oxidative reactivity of Mn- and Fe-oxides and (2) the reductive reactivity of Fe(II)/iron

Keywords： Iron oxides     manganese oxides     reduction     oxidation     complex systems     reaction kinetics and mechanisms    

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Mechanical properties of vanadium-alloyed austempered ductile iron for crankshaft applications

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 3, doi: 10.1007/s11465-023-0746-2

Abstract: This study focused on the development of austempered ductile iron (ADI) with desirable combination of

Keywords： austempered ductile iron (ADI)     vanadium alloying     mechanical properties     crankshafts     retained austenite    

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Scrap Iron Filings assisted nitrate and phosphate removal in low C/N waters using mixed microbial culture

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 4, doi: 10.1007/s11783-020-1358-2

Abstract:

• Microbes enhance denitrification under varying DO concentrations and SIF dosages.

Keywords： Scrap iron filing     Nitrate removal     Phosphate removal     Mixed culture denitrification     Zero valent iron    

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Highly selective and green recovery of lithium ions from lithium iron phosphate powders with ozone

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 6,   Pages 749-758 doi: 10.1007/s11705-022-2261-0

Abstract: Since lithium iron phosphate cathode material does not contain high-value metals other than lithium,strike a balance between recovery efficiency and economic benefits in the recycling of waste lithium ironIron is retained in the leaching residue as iron phosphate, which is easy to recycle.concentration, acid dosage, amount of oxidant, and reaction temperature on the leaching of lithium and ironpotential industrial use of this process and enables the green and efficient recycling of waste lithium iron

Keywords： lithium iron phosphate powder     stoichiometric number     selective leaching     lithium recovery    

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Synthesis of iron(II) complexes with asymmetric N

Wolfgang Bauer, Tanja Ossiander, Birgit Weber

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 3,   Pages 400-408 doi: 10.1007/s11705-018-1753-4

Abstract:

The synthesis of new Schiff base-like ligands with asymmetric substituents pattern and their ironTwo of the ligands and one of the iron(II) complexes were characterized by single crystal X-ray structureOne of the the iron(II) complexes shows spin crossover behavior while the others remain in the high spin

Keywords： iron     Schiff base-like ligands     magnetism     spin crossover     X-ray structures    

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Methanol to propylene: the effect of iridium and iron incorporation on the HZSM-5 catalyst

Alireza MOHAMMADREZAEI, Sadegh PAPARI, Mousa ASADI, Abas NADERIFAR, Reza GOLHOSSEINI

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 3,   Pages 253-258 doi: 10.1007/s11705-012-0902-4

Abstract: The effect of iridium and iron impregnation of HZSM-5 zeolite on the methanol to propylene reaction (The results indicate that HZSM-5 zeolite modified by iron and iridium increased propylene selectivity

Keywords： HZSM-5     promoter     iridium     iron     MTP    

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Continuous dynamic monitoring of a centenary iron bridge for structural modification assessment

Carmelo GENTILE,Antonella SAISI

Frontiers of Structural and Civil Engineering 2015, Volume 9, Issue 1,   Pages 26-41 doi: 10.1007/s11709-014-0284-4

Abstract: A multi-channel continuous dynamic monitoring system has been installed in a centenary iron arch bridgeand crossing the Adda river about 50 km far from Milan, is the most important monument of XIX century iron

Keywords： automated modal identification     continuous dynamic monitoring     environmental/operational effects     iron arch    

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Title Author Date Type Operation

randomized, controlled, open label non-inferiority trial of intravenous ferric carboxymaltose versus ironsucrose in patients with iron deficiency anemia in China

Journal Article

Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:

Dong Wang, Min Tian, Guanglin Cui, Dao Wen Wang

Journal Article

Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice

Journal Article

Prevalence of vitamin D deficiency in girls with idiopathic central precocious puberty

Yue Zhao, Wenjun Long, Caiqi Du, Huanhuan Yang, Shimin Wu, Qin Ning, Xiaoping Luo

Journal Article

Synergistic effects of sodium hypochlorite disinfection and iron-oxidizing bacteria on early corrosionin cast iron pipes

Journal Article

Intestinal Epithelial Axin1 Deficiency Protects Against Colitis via Altered Gut Microbiota

Shari Garrett,Yongguo Zhang,Yinglin Xia,Jun Sun,

Journal Article

Chinmedomics facilitated quality-marker discovery of Sijunzi decoction to treat spleen qi deficiency

Qiqi Zhao, Xin Gao, Guangli Yan, Aihua Zhang, Hui Sun, Ying Han, Wenxiu Li, Liang Liu, Xijun Wang

Journal Article

Performance of iron-air battery with iron nanoparticle-encapsulated C–N composite electrode

Journal Article

Redox reactions of iron and manganese oxides in complex systems

Jianzhi Huang, Huichun Zhang

Journal Article

Mechanical properties of vanadium-alloyed austempered ductile iron for crankshaft applications

Journal Article

Scrap Iron Filings assisted nitrate and phosphate removal in low C/N waters using mixed microbial culture

Journal Article

Highly selective and green recovery of lithium ions from lithium iron phosphate powders with ozone

Journal Article

Synthesis of iron(II) complexes with asymmetric N

Wolfgang Bauer, Tanja Ossiander, Birgit Weber

Journal Article

Methanol to propylene: the effect of iridium and iron incorporation on the HZSM-5 catalyst

Alireza MOHAMMADREZAEI, Sadegh PAPARI, Mousa ASADI, Abas NADERIFAR, Reza GOLHOSSEINI

Journal Article

Continuous dynamic monitoring of a centenary iron bridge for structural modification assessment

Carmelo GENTILE,Antonella SAISI

Journal Article